Shorty receives word from Anita informing him that she wants him to go into the Arizona hills and find Professor Wade, who has discovered a radium mine, but is in a bad way as his guide has died. Shorty sets out at once. The professor meets a stranded actor and they set out together to reach town. They are attacked by Apache Bill and the actor is killed, but the professor crawls to a bunch of cacti and secretes a phial of radium in an old skull. Shorty comes upon the actor's make-up kit and makes up as a wild man and scares Apache Bill, who has found the radium mine. The bandits run away and tell the manager of a side show of the wild man. Shorty's horse runs away and he is found and taken to the circus. Here he is exhibited as a wild man and because of a cold is unable to speak. Later his horse helps Shorty escape and he causes the arrest of the bandits.