O.T.R. (Over The Rhine) is a gritty crime drama set in one of Cincinnati's most notorious and dangerous inner city neighborhoods. Stannus 'Jinx' Jinkens is a successful nightclub owner, and one Mid-West's most powerful crime lords. His sister, detective Denise Jinkens works in the Cincinnati's Police homicide unit. Temperatures come to a boil on the streets of Cincinnati as this brother and sister stand on completely opposite sides of the law and prepare for an inevitable all out war in Over The Rhine.